Esomet-LSR Capsule

Esomeprazole 40 mg+ Levosulpiride 75 mg SR Capsules

Esomet LSR

Esomet-LSR Capsule

Esomeprazole 40 mg+ Levosulpiride 75 mg SR Capsules

Esomeprazole 40 mg+ Levosulpiride 75 mg SR Capsules Esomeprazole 40 mg It is a proton pump inhibitors that suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase in the gastric parietal cell. Indications Gastroesophageal reflux disease. Eradication of Helicobacter pylori in combine with appropriate antibacterial regimens. Healing and maintenance of erosive oesophagitis.   […]

MRP : Rs.170/-

Package : 10x10 Alu-Alu Tablet

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Product Description

Esomeprazole 40 mg+ Levosulpiride 75 mg SR Capsules

Esomeprazole 40 mg

It is a proton pump inhibitors that suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase in the gastric parietal cell.

Indications

Gastroesophageal reflux disease. Eradication of Helicobacter pylori in combine with appropriate antibacterial regimens. Healing and maintenance of erosive oesophagitis.

 

Contraindications

Hypersensitivity to any component of the formulation.

Safety Profile

Reduced dose in hepatic insufficiency. Should be taken one hour before meals.

Adverse Effects

Headache, flatulence, Dry mouth, alkaline phosphatase.

Drug Interactions

Esomeprazole may interfere with the absorption of drug where gastric PH is an important determinant of bioavailability e.g. ketoconazole, iron salts and digoxin.

Dosage

Gastroesophageal reflux disease, healing of erosive esophagitis: 20 mg or 40 mg once daily for 4 to 8 weeks. Maintenance of healing of erosive oesophagitis: 20 mg once daily. Symptomatic gastroesophageal reflux: 20 mg once daily for 4 weeks. H-pylori eradication to reduce the risk of duodenal with amoxicillin, 11g twice daily and clarithromycin 500 mg twice daily for 10 days.

Levosulpiride 75 mg

Sulpiride is a selective dopamine D2 antagonist having both antipsychotic and antidepressant activity.

Indications

In treatment of antidepressant, also used in schizophrenia.

Contraindications

Hypersensitivity, Parkinson’s disease.

Safety Profile

Reduced dose is recommended in renal impairment Patients.

Adverse Effects

Menstrual disorders, amenorrhoea galactorrhea, breast engorgement palpitations, hepatotoxicity.

Dosage

Adults: Depression: 200 mg- 1000 mg per day. Schizophrenia: 800 mg – 3200 mg per day.